Treatments

Chemotherapy: How It Works, Side Effects & What to Expect

Chemotherapy uses drugs that kill or slow the growth of rapidly dividing cells, including cancer cells. It remains one of the most widely used cancer treatments and can be given alone or alongside surgery, radiation, or newer targeted and immune therapies.

3 min readLast reviewed August 1, 2026Medically reviewed by: GetOnco Medical Review Team

Summary

Chemotherapy uses cell-killing drugs to treat cancer, either as the main treatment or alongside surgery, radiation, or other therapies, with regimens tailored to cancer type and patient health.

Key takeaways

  • Chemotherapy drugs interfere with cell division to kill or slow cancer growth.
  • It can be given before or after other treatments, or as the primary approach.
  • Doctors select drugs and doses based on cancer type, stage, and organ function.
  • Side effects are common but are managed with supportive care and dose adjustments.
  • Regular monitoring during treatment helps catch and address complications early.

What it is

Chemotherapy refers to a broad group of medicines that interfere with cell division, causing cancer cells to die or stop multiplying. Drugs can be given intravenously, as pills, or through injections, often in cycles that alternate treatment with recovery periods so the body can repair healthy tissue.

What it means for you

If chemotherapy is recommended, your team will explain the specific drugs, expected side effects, and schedule. Understanding the goal—cure, control, or symptom relief—helps set realistic expectations for treatment.

Testing

Before treatment, blood counts, organ function tests, and imaging confirm the cancer's extent and whether the body can safely tolerate specific drugs. Ongoing blood tests during treatment monitor for low counts and organ effects.

Associated cancer types

Chemotherapy is used across many cancers, including breast, lung, colorectal, ovarian, testicular, and blood cancers such as leukaemia and lymphoma. It may be the primary treatment or combined with surgery and radiation depending on cancer type and stage.

Treatment options

Options range from single-drug regimens to multi-drug combinations, given intravenously or orally, often in cycles. Supportive medicines for nausea, infection prevention, and blood count support are typically built into the plan.

Questions patients ask

  • What is the goal of this chemotherapy—cure, control, or symptom relief?
  • Which side effects should I watch for and when should I call the clinic?
  • How will you monitor whether the chemotherapy is working?
  • Can this regimen affect my fertility or long-term health?
  • What supportive medicines will I receive alongside chemotherapy?

Frequently asked questions

Will I lose my hair during chemotherapy?

Hair loss depends on the specific drugs used; some regimens cause it and others do not. Your oncology team can tell you what to expect with your particular treatment plan.

How long does a course of chemotherapy last?

Treatment length varies widely, from a few weeks to several months, depending on cancer type, stage, and how well the cancer responds.

Can I work while having chemotherapy?

Many people continue working, often adjusting hours around treatment days and fatigue, but this depends on the regimen and individual tolerance.

References

  1. 1.Chemotherapy to Treat CancerNational Cancer Institute
  2. 2.ChemotherapyESMO
  3. 3.Chemotherapy PrinciplesASCO
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Medically reviewed by:GetOnco Medical Review Team — Oncology-trained clinicians and medical editors

Last reviewed August 1, 2026

Medical disclaimer

Educational information only. GetOnco is software, not a medical provider, and does not diagnose disease or recommend treatments. Always discuss your situation with qualified healthcare professionals.